META-BRAIN Magnetoelectric and Ultrasonic Technology for Advanced Brain Modulation

META-BRAIN Magnetoelectric and Ultrasonic Technology for Advanced Brain Modulation


META-BRAIN is a Horizon Europe project uniting seven expert partners across nanotechnology, nano and microelectronics, new materials, brain science, clinical expertise, and computation. Its goal is to achieve precise spatio-temporal control of brain activity through the use of remote magnets and/or ultrasound.

To this end, META-BRAIN —MagnetoElectric and Ultrasonic Technology for Advanced BRAIN modulation— will introduce state-of-the-art technological developments centered on two innovative strategies: non-invasive magnetoelectric stimulation utilizing magnetoelectric nanoparticles, and minimally invasive ultrasound stimulation.

META-BRAIN will develop brain stimulation technologies with significant potential to restore physiological brain activity patterns. These innovations hold promise not only for therapeutic applications but also for sensory replacement as a brain interface.

metabrain project investigation brain




EU countries




million EUR in funding


Work Packages

Social Impact

META-BRAIN’s semi-invasive approaches could significantly impact the treatment of various prevalent medical conditions associated with altered electrical activity in neuronal tissue, such as consciousness disorders, stroke, epilepsy, depression, Parkinson’s Disease and traumatic brain injury.

Scientific Impact

META-BRAIN will generate high-quality novel insights and pave the way for advancements in the research and technology of stimulating brain tissue activity.

Specific Objectives

META-BRAIN is dedicated to advancing technology for a deeper understanding of brain activity, addressing neurological dysfunction, and promoting physiological recovery


Developing, testing, and validating nanostructures with magnetoelectric properties to modulate brain activity and assess their effectiveness in regulating cortical activity


Investigating brain stimulation using novel devices that use ultrasound, analyzing their short and long-term effects on brain activity.


Designing devices for precise measurement of brain activity and developing computational simulation techniques to better understand brain electromagnetic fields.


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